New publication: BashTheBug works! Philip Fowler, 20th May 202219th July 2022 Yesterday eLife published the first paper from our citizen science project, BashTheBug, which was launched in April 2017 on the Zooniverse platform. (Update on 19 July 2022: the final formatted version of the paper has been posted on eLife). Through BashTheBug we asked for volunteers to classify images of M. tuberculosis growing on a range of concentrations of 13 different antibiotics. The images were derived from photographs of 96-well plates taken after two weeks incubation by the CRyPTIC tuberculosis project. Each image is shown up to 17 times to different volunteers so we can obtain a consensus. In total the volunteers did over 4.7 million classifications, and by examining a subset of images, this paper determines how best to obtain the consensus and how reproducible and accurate the crowd of volunteers are. Photograph of 96-well plate collected by the CRyPTIC project and the CRyPTIC partner laboratories who contributed images to this study. Share this: Click to share on X (Opens in new window) X Click to share on Bluesky (Opens in new window) Bluesky Click to email a link to a friend (Opens in new window) Email Click to share on LinkedIn (Opens in new window) LinkedIn Click to share on Mastodon (Opens in new window) Mastodon Related antimicrobial resistance citizen science clinical microbiology publication research tuberculosis
antimicrobial resistance New Publication: Structure of MmpL3 21st July 202121st July 2021 Oliver Adams successfully elucidated the structure of the M. tuberculosis MmpL3 membrane transporter using cryo-EM… Share this: Click to share on X (Opens in new window) X Click to share on Bluesky (Opens in new window) Bluesky Click to email a link to a friend (Opens in new window) Email Click to share on LinkedIn (Opens in new window) LinkedIn Click to share on Mastodon (Opens in new window) Mastodon Read More
SARS-CoV-2 pipeline live on EIT Pathogena 28th January 202528th January 2025 Back in the SARS-CoV-2 pandemic we worked closely with ORACLE Corp to build and deploy… Share this: Click to share on X (Opens in new window) X Click to share on Bluesky (Opens in new window) Bluesky Click to email a link to a friend (Opens in new window) Email Click to share on LinkedIn (Opens in new window) LinkedIn Click to share on Mastodon (Opens in new window) Mastodon Read More
publication New Publication: Flexible Gates Generate Occluded Intermediates in the Transport Cycle of LacY 8th November 2013 In this paper we examine how the lactose permease, LacY, changes its structure to shuttle… Share this: Click to share on X (Opens in new window) X Click to share on Bluesky (Opens in new window) Bluesky Click to email a link to a friend (Opens in new window) Email Click to share on LinkedIn (Opens in new window) LinkedIn Click to share on Mastodon (Opens in new window) Mastodon Read More