New preprint: ONT sequencing is comparable to Illumina sequencing for M. tuberculosis Philip Fowler, 9th April 20269th April 2026 In this preprint, we compare the differences when Mycobacterial samples are sequenced with either long-… Continue Reading
clinical microbiology New paper: Addressing pandemic-wide systematic errors in the SARS-CoV-2 phylogeny Philip Fowler, 9th February 20269th February 2026 Zam Iqbal, at the University of Bath, led this epic study published today in Nature… Continue Reading
New preprint: evaluating a laboratory workflow for sequencing Mycobacteria using long-read sequencing Philip Fowler, 7th February 20269th April 2026 In this preprint, we describe and evaluate a laboratory workflow for sequencing Mycobacterial samples using… Continue Reading
antimicrobial resistance New paper: how well can we predict AMR in tuberculosis samples? Philip Fowler, 16th December 202516th December 2025 This paper just published in Microbial Genomics examines how well our software tool, gnomonicus, predicts… Continue Reading
antimicrobial resistance New preprint: Predicting pyrazinamide resistance in M. tuberculosis using a graph convolutional network Philip Fowler, 29th October 202530th October 2025 In previous work we’ve used “traditional” machine-learning approaches, like XGBoost, to learn and therefore predict… Continue Reading
New paper: Evaluating 12 WGS analysis pipelines for MBTC Philip Fowler, 21st October 202529th October 2025 Ruan Spies did a careful systematic analysis of the publicly-available pipelines that claimed to process… Continue Reading