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Predicting antibiotic resistance de novo

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Fowler Lab
Fowler Lab

Predicting antibiotic resistance de novo

Category: tuberculosis

New preprint: ONT sequencing is comparable to Illumina sequencing for M. tuberculosis

Philip Fowler, 9th April 20269th April 2026

In this preprint, we compare the differences when Mycobacterial samples are sequenced with either long-…

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New preprint: evaluating a laboratory workflow for sequencing Mycobacteria using long-read sequencing

Philip Fowler, 7th February 20269th April 2026

In this preprint, we describe and evaluate a laboratory workflow for sequencing Mycobacterial samples using…

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antimicrobial resistance

New paper: how well can we predict AMR in tuberculosis samples?

Philip Fowler, 16th December 202516th December 2025

This paper just published in Microbial Genomics examines how well our software tool, gnomonicus, predicts…

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antimicrobial resistance

New preprint: Predicting pyrazinamide resistance in M. tuberculosis using a graph convolutional network

Philip Fowler, 29th October 202530th October 2025

In previous work we’ve used “traditional” machine-learning approaches, like XGBoost, to learn and therefore predict…

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New paper: Evaluating 12 WGS analysis pipelines for MBTC

Philip Fowler, 21st October 202529th October 2025

Ruan Spies did a careful systematic analysis of the publicly-available pipelines that claimed to process…

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Dylan’s bedaquline paper one of the most read in Microbial Genomics in September!

Philip Fowler, 20th October 202520th October 2025

Received a lovely email from Dr Peter Cotgreave who is the Chief Executive of the…

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