New Publication: Protein crowding affects the organisation of ion channels Philip Fowler, 3rd December 201729th September 2018 0 shares Protein crowding and lipid complexity influence the nanoscale dynamic organization of ion channels in cell membranes It is difficult to look at the dynamic spatial organisation of ion channels in cell membranes, but this is something coarse-grained molecular dynamics simulations can offer insights. This work, led by Anna Duncan, shows how altering the lipid composition of the membrane changes the large-scale organisation of the Kir2.2 channels. Building on some previous work, we also show how the membrane properties, such as stiffness, are also altered. The latter relies on some python code that you can download from GitHub. The paper is free to download. Share this:Twitter Related publication research
New publication: WHO catalogue of Mycobacterium tuberculosis resistant mutations 28th March 202228th March 2022 The CRyPTIC project collecting over 20,000 clinical samples of TB and for each, sequencing its… Share this:Twitter Read More
antimicrobial resistance New print: Epidemiological cutoff values for a 96-well broth microdilution plate for M. tuberculosis 5th March 202122nd March 2021 In this preprint, the CRyPTIC project proposes the maximum value of minimum inhibitory concentration (MIC)… Share this:Twitter Read More
antimicrobial resistance New paper: predicting pyrazinamide resistance 20th March 202420th March 2024 This paper has finally been published and you can find it here. It had a… Share this:Twitter Read More