New publication: WHO catalogue of Mycobacterium tuberculosis resistant mutations Philip Fowler, 28th March 202228th March 2022 The CRyPTIC project collecting over 20,000 clinical samples of TB and for each, sequencing its… Continue Reading
antimicrobial resistance New preprint: Predicting antibiotic resistance in complex protein targets Philip Fowler, 4th January 20224th January 2022 In this preprint, which Alice has been working on for several years, we show how… Continue Reading
antimicrobial resistance New Publication: Structure of MmpL3 Philip Fowler, 21st July 202121st July 2021 Oliver Adams successfully elucidated the structure of the M. tuberculosis MmpL3 membrane transporter using cryo-EM… Continue Reading
antimicrobial resistance Postdoctoral position advertised Philip Fowler, 17th May 202117th May 2021 Through the CompBioMed2 EU Centre of Excellence project I have funding to appoint a postdoctoral… Continue Reading
antimicrobial resistance New print: Epidemiological cutoff values for a 96-well broth microdilution plate for M. tuberculosis Philip Fowler, 5th March 202122nd March 2021 In this preprint, the CRyPTIC project proposes the maximum value of minimum inhibitory concentration (MIC)… Continue Reading
antimicrobial resistance New publication: Phylogenetically informative mutations in genes implicated in antibiotic resistance in Mycobacterium tuberculosis complex Philip Fowler, 9th March 202016th March 2020 Although the population structure M. tuberculosis is clonal, one must be careful when inferring the… Continue Reading