New preprint: comparing different genetics analysis pipelines for tuberculosis Philip Fowler, 13th January 202513th January 2025 Ruan Spies has done a careful systematic comparison of the current genetics pipelines that purport to take raw genetic reads from a clinical sample containing M. tuberculosis (or Mycobacteria generally) and process them to produce a putative genome from which an antibiogram can be predicted. He couldn’t get some of the pipelines to work but of the others, with a few exceptions, AMR prediction performance was often similar. The non-functional features of EIT Pathogena stand-out; these are things like resilience, ease-of-use, speed and security. You can read about it here. Share this: Share on X (Opens in new window) X Share on Bluesky (Opens in new window) Bluesky Email a link to a friend (Opens in new window) Email Share on LinkedIn (Opens in new window) LinkedIn Share on Mastodon (Opens in new window) Mastodon Related antimicrobial resistance clinical microbiology gpas publication research tuberculosis
New paper: Evaluating 12 WGS analysis pipelines for MBTC 21st October 202529th October 2025 Ruan Spies did a careful systematic analysis of the publicly-available pipelines that claimed to process… Share this: Share on X (Opens in new window) X Share on Bluesky (Opens in new window) Bluesky Email a link to a friend (Opens in new window) Email Share on LinkedIn (Opens in new window) LinkedIn Share on Mastodon (Opens in new window) Mastodon Read More
New refereed preprint: BashTheBug 31st March 202231st March 2022 BashTheBug is a citizen science project hosted on the Zooniverse platform that we launched in… Share this: Share on X (Opens in new window) X Share on Bluesky (Opens in new window) Bluesky Email a link to a friend (Opens in new window) Email Share on LinkedIn (Opens in new window) LinkedIn Share on Mastodon (Opens in new window) Mastodon Read More
antimicrobial resistance New preprint: rapidly and reproducibly building resistant catalogues for M. tuberculosis 3rd October 202530th October 2025 The CRyPTIC project carried out many exciting research projects but it never quite got around… Share this: Share on X (Opens in new window) X Share on Bluesky (Opens in new window) Bluesky Email a link to a friend (Opens in new window) Email Share on LinkedIn (Opens in new window) LinkedIn Share on Mastodon (Opens in new window) Mastodon Read More