New preprint: comparing different genetics analysis pipelines for tuberculosis Philip Fowler, 13th January 202513th January 2025 Ruan Spies has done a careful systematic comparison of the current genetics pipelines that purport to take raw genetic reads from a clinical sample containing M. tuberculosis (or Mycobacteria generally) and process them to produce a putative genome from which an antibiogram can be predicted. He couldn’t get some of the pipelines to work but of the others, with a few exceptions, AMR prediction performance was often similar. The non-functional features of EIT Pathogena stand-out; these are things like resilience, ease-of-use, speed and security. You can read about it here. Share this: Click to share on X (Opens in new window) X Click to share on Bluesky (Opens in new window) Bluesky Click to email a link to a friend (Opens in new window) Email Click to share on LinkedIn (Opens in new window) LinkedIn Click to share on Mastodon (Opens in new window) Mastodon Related antimicrobial resistance clinical microbiology gpas publication research tuberculosis
antimicrobial resistance New Publication: Structure of MmpL3 21st July 202121st July 2021 Oliver Adams successfully elucidated the structure of the M. tuberculosis MmpL3 membrane transporter using cryo-EM… Share this: Click to share on X (Opens in new window) X Click to share on Bluesky (Opens in new window) Bluesky Click to email a link to a friend (Opens in new window) Email Click to share on LinkedIn (Opens in new window) LinkedIn Click to share on Mastodon (Opens in new window) Mastodon Read More
publication New Publication: Energetics of Multi-Ion Conduction Pathways in Potassium Ion Channels 31st October 2013 Can we predict the conductance of a potassium ion channel from an experimental structure? In this… Share this: Click to share on X (Opens in new window) X Click to share on Bluesky (Opens in new window) Bluesky Click to email a link to a friend (Opens in new window) Email Click to share on LinkedIn (Opens in new window) LinkedIn Click to share on Mastodon (Opens in new window) Mastodon Read More
publication New Publication: Detailed examination of a single conduction event in a potassium channel. 15th October 2013 What can we learn using computational methods about how potassium ions and water molecules move… Share this: Click to share on X (Opens in new window) X Click to share on Bluesky (Opens in new window) Bluesky Click to email a link to a friend (Opens in new window) Email Click to share on LinkedIn (Opens in new window) LinkedIn Click to share on Mastodon (Opens in new window) Mastodon Read More