New publication: Phylogenetically informative mutations in genes implicated in antibiotic resistance in Mycobacterium tuberculosis complex Philip Fowler, 9th March 202016th March 2020 Although the population structure M. tuberculosis is clonal, one must be careful when inferring the effect of individual mutations on the effect of an antibiotic. Purely because a mutation appears to define a phylogeny does not mean it has no effect on the minimum inhibitory concentration. Read more here (Open Access). Share this:TwitterBlueskyEmailLinkedInMastodon Related antimicrobial resistance clinical microbiology publication research tuberculosis
New preprint: Including minor alleles improves fluoroquinolone resistance prediction 10th November 202217th November 2022 Fluoroquinolones are used to treat both normal and drug resistant tuberculosis and therefore being able… Share this:TwitterBlueskyEmailLinkedInMastodon Read More
antimicrobial resistance BashTheBug at the Science Museum 29th March 20175th August 2018 A group of us from Modernising Medical Microbiology went to the Science Museum in London… Share this:TwitterBlueskyEmailLinkedInMastodon Read More
antimicrobial resistance BioExcel Alchemical Free Energy workshop 17th June 2019 Last month I was invited to give a talk on using alchemical free energy methods… Share this:TwitterBlueskyEmailLinkedInMastodon Read More