New publication: Phylogenetically informative mutations in genes implicated in antibiotic resistance in Mycobacterium tuberculosis complex Philip Fowler, 9th March 202016th March 2020 Although the population structure M. tuberculosis is clonal, one must be careful when inferring the effect of individual mutations on the effect of an antibiotic. Purely because a mutation appears to define a phylogeny does not mean it has no effect on the minimum inhibitory concentration. Read more here (Open Access). Share this:Twitter Related antimicrobial resistance clinical microbiology publication research tuberculosis
antimicrobial resistance New preprint: Deciphering bedaquiline and clofazimine resistance in tuberculosis 22nd March 202122nd March 2021 In this preprint we examine 14,151 clinical isolates drawn from the CRyPTIC dataset. Each isolate… Share this:Twitter Read More
antimicrobial resistance New publication: Reconciling the potentially irreconcilable? Genotypic and phenotypic amoxicillin-clavulanate resistance in Escherichia coli. 30th March 202022nd August 2020 Clinical microbiology often assumes a sample is resistant or susceptible. Making such a classification relies… Share this:Twitter Read More
publication New Publication: Proteins Alter the Stiffness of Membranes 23rd September 201629th September 2018 Although there have been many studies of proteins whose primary function is to ‘sculpt’ the… Share this:Twitter Read More