New publication: Phylogenetically informative mutations in genes implicated in antibiotic resistance in Mycobacterium tuberculosis complex Philip Fowler, 9th March 202016th March 2020 Although the population structure M. tuberculosis is clonal, one must be careful when inferring the effect of individual mutations on the effect of an antibiotic. Purely because a mutation appears to define a phylogeny does not mean it has no effect on the minimum inhibitory concentration. Read more here (Open Access). Share this:TwitterBlueskyEmailLinkedInMastodon Related antimicrobial resistance clinical microbiology publication research tuberculosis
antimicrobial resistance Can medical microbiology become a big data science? Lessons from CRyPTIC 11th March 202511th March 2025 The CRyPTIC project ran from 2017 to around 2022 and in that time collected over… Share this:TwitterBlueskyEmailLinkedInMastodon Read More
antimicrobial resistance BioExcel Alchemical Free Energy workshop 17th June 2019 Last month I was invited to give a talk on using alchemical free energy methods… Share this:TwitterBlueskyEmailLinkedInMastodon Read More
antimicrobial resistance New publication: Validating a bespoke 96-well plate for high-throughput drug susceptibility testing of M. tuberculosis 28th August 201829th September 2018 This paper, published in Antimicrobial Agents and Chemotherapy, determines the reproducibility and accuracy of minimum… Share this:TwitterBlueskyEmailLinkedInMastodon Read More