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Fowler Lab
Fowler Lab

Predicting antibiotic resistance de novo

New publication: Phylogenetically informative mutations in genes implicated in antibiotic resistance in Mycobacterium tuberculosis complex

Philip Fowler, 9th March 202016th March 2020

Although the population structure M. tuberculosis is clonal, one must be careful when inferring the effect of individual mutations on the effect of an antibiotic. Purely because a mutation appears to define a phylogeny does not mean it has no effect on the minimum inhibitory concentration.

Read more here (Open Access).

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