New Publication: Protein crowding affects the organisation of ion channels Philip Fowler, 3rd December 201729th September 2018 Protein crowding and lipid complexity influence the nanoscale dynamic organization of ion channels in cell membranes It is difficult to look at the dynamic spatial organisation of ion channels in cell membranes, but this is something coarse-grained molecular dynamics simulations can offer insights. This work, led by Anna Duncan, shows how altering the lipid composition of the membrane changes the large-scale organisation of the Kir2.2 channels. Building on some previous work, we also show how the membrane properties, such as stiffness, are also altered. The latter relies on some python code that you can download from GitHub. The paper is free to download. Share this: Click to share on X (Opens in new window) X Click to share on Bluesky (Opens in new window) Bluesky Click to email a link to a friend (Opens in new window) Email Click to share on LinkedIn (Opens in new window) LinkedIn Click to share on Mastodon (Opens in new window) Mastodon Related publication research
publication New publication: Insights into the structural nature of the transition state in the Kir channel gating pathway. 2nd February 2015