New publication: determining novel mechanisms of bedaquiline resistance Philip Fowler, 30th March 20235th April 2023 A new paper with Lindsay Sonnenkalb as first-author has just been published in The Lancet… Continue Reading
New preprint: Including minor alleles improves fluoroquinolone resistance prediction Philip Fowler, 10th November 202217th November 2022 Fluoroquinolones are used to treat both normal and drug resistant tuberculosis and therefore being able… Continue Reading
New publication: BashTheBug works! Philip Fowler, 20th May 202219th July 2022 Yesterday eLife published the first paper from our citizen science project, BashTheBug, which was launched… Continue Reading
New publication: WHO catalogue of Mycobacterium tuberculosis resistant mutations Philip Fowler, 28th March 202228th March 2022 The CRyPTIC project collecting over 20,000 clinical samples of TB and for each, sequencing its… Continue Reading
antimicrobial resistance New preprint: Predicting antibiotic resistance in complex protein targets Philip Fowler, 4th January 20224th January 2022 In this preprint, which Alice has been working on for several years, we show how… Continue Reading
antimicrobial resistance New Publication: Structure of MmpL3 Philip Fowler, 21st July 202121st July 2021 Oliver Adams successfully elucidated the structure of the M. tuberculosis MmpL3 membrane transporter using cryo-EM… Continue Reading