New publication: Validating a bespoke 96-well plate for high-throughput drug susceptibility testing of M. tuberculosis Philip Fowler, 28th August 201829th September 2018 This paper, published in Antimicrobial Agents and Chemotherapy, determines the reproducibility and accuracy of minimum inhibitory concentrations for a panel of 14 different anti-TB compounds using a specifically designed 96-well plate (called UKMYC5) manufactured by Thermo Fisher. Since the UKMYC5 plate is being used by the CRyPTIC consortium to measure the drug susceptibility profiles of >30,000 clinical TB samples collected worldwide between now and 2020, this manuscript lays the foundations for this large and ambitious tuberculosis research project. It is free to read and download, and the paper briefly mentions my AMyGDA software which we will be using as an independent measuring technique to quality control the measurements made by the laboratory scientists. You can download and AMyGDA software from here. A manuscript is currently under review – you can read a preprint here. The bacterial growth on the UKMYC5 plates are also being classified by a Citizen Science project I have setup, BashTheBug. Share this:Twitter Related antimicrobial resistance clinical microbiology publication tuberculosis
antimicrobial resistance Accelerating Oxford Nanopore basecalling 26th January 20175th August 2018 It looks innocuous sitting on the desk, an Oxford Nanopore MinION, but it can produce… Share this:Twitter Read More
antimicrobial resistance BashTheBug Coordinator post advertised 15th November 2019 We are advertising for a Part-time Citizen Science Project Co-ordinator to come and work with… Share this:Twitter Read More
publication New Publication: Energetics of Multi-Ion Conduction Pathways in Potassium Ion Channels 31st October 2013 Can we predict the conductance of a potassium ion channel from an experimental structure? In this… Share this:Twitter Read More