antimicrobial resistance New preprint: compensatory mutations are associated with increased growth in resistant samples of M. tuberculosis. Philip Fowler, 22nd June 20238th December 2023 In this preprint, Viki Brunner shows how, using the large CRyPTIC dataset, she can recapitulate… Continue Reading
New publication: detecting minor populations important for predicting fluoroquinolone resistance Philip Fowler, 5th April 20238th December 2023 When predicting if an infection is resistant or susceptible to a specific antibiotic, it is… Continue Reading
New publication: determining novel mechanisms of bedaquiline resistance Philip Fowler, 30th March 20235th April 2023 A new paper with Lindsay Sonnenkalb as first-author has just been published in The Lancet… Continue Reading
Viki Brunner wins poster prize Philip Fowler, 23rd November 202223rd November 2022 The whole group attended the first INEOS Oxford Institute meeting on Multidisciplinary Approaches to AMR… Continue Reading
New preprint: Including minor alleles improves fluoroquinolone resistance prediction Philip Fowler, 10th November 202217th November 2022 Fluoroquinolones are used to treat both normal and drug resistant tuberculosis and therefore being able… Continue Reading
New publication: Predicting antibiotic resistance in complex protein targets using alchemical free energy methods Philip Fowler, 26th August 202224th October 2022 In this paper, Alice Brankin calculates how different mutations in the DNA gyrase affect the… Continue Reading