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Predicting antibiotic resistance de novo

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Fowler Lab
Fowler Lab

Predicting antibiotic resistance de novo

Category: research

antimicrobial resistance

New paper: quantitative measurement of effect of mutations on antibiotics in M. tuberculosis

Philip Fowler, 15th January 202415th January 2024

The CRyPTIC project played a major role in the release by the WHO of their…

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antimicrobial resistance

New preprint: Infection Inspection

Philip Fowler, 12th December 202312th December 2023

Some great work by Conor Feehily, Nicole Stoesser and others, including collaborators from the Department…

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Desirable features for any antibiotic resistance catalogue

Philip Fowler, 31st October 202331st October 2023

In the past few years a growing number of catalogues containing mutations associated with resistance…

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antimicrobial resistance

New preprint: compensatory mutations are associated with increased growth in resistant samples of M. tuberculosis.

Philip Fowler, 22nd June 20238th December 2023

In this preprint, Viki Brunner shows how, using the large CRyPTIC dataset, she can recapitulate…

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New publication: determining novel mechanisms of bedaquiline resistance

Philip Fowler, 30th March 20235th April 2023

A new paper with Lindsay Sonnenkalb as first-author has just been published in The Lancet…

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New preprint: Including minor alleles improves fluoroquinolone resistance prediction

Philip Fowler, 10th November 202217th November 2022

Fluoroquinolones are used to treat both normal and drug resistant tuberculosis and therefore being able…

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