New preprint: automatically building a better bedaquiline catalogue Philip Fowler, 31st January 202531st January 2025 A catalogue recording whether individual mutations confer resistance or not to specified antibiotics is a… Continue Reading
New preprint: comparing different genetics analysis pipelines for tuberculosis Philip Fowler, 13th January 202513th January 2025 Ruan Spies has done a careful systematic comparison of the current genetics pipelines that purport… Continue Reading
New preprint: validating antibiotic resistance prediction in our Myco pipeline Philip Fowler, 9th November 202413th January 2025 Over the last 18 months or so we’ve been designing, coding and testing a Mycobacterial… Continue Reading
antimicrobial resistance New preprint: predicting rifampicin resistance Philip Fowler, 16th August 202416th August 2024 In this preprint we train a series of machine learning models on protein mutations found… Continue Reading
antimicrobial resistance Updating the Grammar for Antimicrobial Resistance Catalogues Philip Fowler, 18th July 202418th July 2024 This blog updates an old (and now out of date) post describing the grammar we’ve… Continue Reading
antimicrobial resistance New paper: predicting pyrazinamide resistance Philip Fowler, 20th March 202420th March 2024 This paper has finally been published and you can find it here. It had a… Continue Reading