antimicrobial resistance New paper: predicting rifampicin resistance via free energy simulation Philip Fowler, 23rd September 20253rd October 2025 This work was carried out by Xibei Zhang, who is doing her PhD with Peter… Continue Reading
antimicrobial resistance New paper: automatically and reproducibly building a catalogue bedaquline resistance-associated variants Philip Fowler, 18th June 20251st July 2025 Dylan Adlard‘s paper describing how we can rapidly automatically build catalogues of bedaquiline resistance-associated variants… Continue Reading
New preprint: automatically building a better bedaquiline catalogue Philip Fowler, 31st January 202531st January 2025 A catalogue recording whether individual mutations confer resistance or not to specified antibiotics is a… Continue Reading
New preprint: comparing different genetics analysis pipelines for tuberculosis Philip Fowler, 13th January 202513th January 2025 Ruan Spies has done a careful systematic comparison of the current genetics pipelines that purport… Continue Reading
New preprint: validating antibiotic resistance prediction in our Myco pipeline Philip Fowler, 9th November 202413th January 2025 Over the last 18 months or so we’ve been designing, coding and testing a Mycobacterial… Continue Reading
antimicrobial resistance New preprint: predicting rifampicin resistance Philip Fowler, 16th August 202416th August 2024 In this preprint we train a series of machine learning models on protein mutations found… Continue Reading