I have a project advertised as part of the DPhil in Computational Discovery programme at the University of Oxford to start in October 2023. This programme is jointly run with IBM and benefits from their applied research in machine learning and other shared areas of interest. The project (Project 6) aims to develop graph-based convolutional […]
Congratulations Dr Brankin!
Alice successfully defended her thesis “Predicting Fluoroquinolone Resistance in Mycobacterium tuberculosis” yesterday. Her examiners were Professor Philip Biggin and Dr Esther Robinson. Much of Alice’s research was done during various SARS-CoV-2 lockdowns and I doubt she thought at the start she’d be using Microsoft Teams so much. Despite this she has produced some excellent research and […]
More good news for the group! Philip was awarded an Associate Professorship by the Nuffield Department of Medicine along with two other researchers.
The whole group attended the first INEOS Oxford Institute meeting on Multidisciplinary Approaches to AMR on Tuesday 22 November 2022. Great to hear how different research groups around Oxford (and elsewhere) are helping to tackle AMR. Best of all though, Viki Brunner won one of the poster prizes for her poster on Compensatory mutations in […]
From left to right: Dylan, Alice, Charlotte, Matty and Phil (Viktoria had only just left the month before) See Members page.
In this preprint, which Alice has been working on for several years, we show how alchemical free energy methods can predict whether an amino acid mutation confers resistance to an antitubercular, but only in cases where the change in binding free energy is large. This is mainly because the confidence limits on the change in […]