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Fowler Lab
Fowler Lab

Predicting antibiotic resistance de novo

New grant: Ox4TB

Philip Fowler, 17th March 202517th March 2025

Very pleased to announce that I am a co-investigator on the recently announced Oxford4TB project that has been funded by the Ineos Oxford Institute for antimicrobial research (IOI). The project will received £5 million over three years and the main aim is to develop new therapies for multi-drug resistant tuberculosis. We will be guiding the selection of targets and leads using our large dataset of >50k clinical tuberculosis samples. Each sample has phenotypic drug susceptibility testing and whole genome data so we will be able to e.g. check there are no mutations in circulation that could lead to resistance of any new compound. I will be advertising a post to work on this project in a few months time.

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