New grant: Ox4TB Philip Fowler, 17th March 202517th March 2025 Very pleased to announce that I am a co-investigator on the recently announced Oxford4TB project that has been funded by the Ineos Oxford Institute for antimicrobial research (IOI). The project will received £5 million over three years and the main aim is to develop new therapies for multi-drug resistant tuberculosis. We will be guiding the selection of targets and leads using our large dataset of >50k clinical tuberculosis samples. Each sample has phenotypic drug susceptibility testing and whole genome data so we will be able to e.g. check there are no mutations in circulation that could lead to resistance of any new compound. I will be advertising a post to work on this project in a few months time. Share this: Click to share on X (Opens in new window) X Click to share on Bluesky (Opens in new window) Bluesky Click to email a link to a friend (Opens in new window) Email Click to share on LinkedIn (Opens in new window) LinkedIn Click to share on Mastodon (Opens in new window) Mastodon Related antimicrobial resistance clinical microbiology tuberculosis
New publication: WHO catalogue of Mycobacterium tuberculosis resistant mutations 28th March 202228th March 2022 The CRyPTIC project collecting over 20,000 clinical samples of TB and for each, sequencing its… Share this: Click to share on X (Opens in new window) X Click to share on Bluesky (Opens in new window) Bluesky Click to email a link to a friend (Opens in new window) Email Click to share on LinkedIn (Opens in new window) LinkedIn Click to share on Mastodon (Opens in new window) Mastodon Read More
antimicrobial resistance New Publication: Predicting whether mutations confer resistance to an antibiotic 5th January 201829th September 2018 Due to the rise of antibiotic resistance, it is increasingly important that your clinician knows… Share this: Click to share on X (Opens in new window) X Click to share on Bluesky (Opens in new window) Bluesky Click to email a link to a friend (Opens in new window) Email Click to share on LinkedIn (Opens in new window) LinkedIn Click to share on Mastodon (Opens in new window) Mastodon Read More
New preprint: automatically building a better bedaquiline catalogue 31st January 202531st January 2025 A catalogue recording whether individual mutations confer resistance or not to specified antibiotics is a… Share this: Click to share on X (Opens in new window) X Click to share on Bluesky (Opens in new window) Bluesky Click to email a link to a friend (Opens in new window) Email Click to share on LinkedIn (Opens in new window) LinkedIn Click to share on Mastodon (Opens in new window) Mastodon Read More