New publication: CRyPTIC Data Compendium Philip Fowler, 16th August 202216th August 2022 The large and comprehensive dataset of clinical tuberculosis isolates collected by the CRyPTIC project is described in detail by this paper, just published in PLoS Biology. Each isolate was whole genome sequenced and had its minimum inhibitory concentration to 13 different antibiotics measured using a bespoke 96-well broth microdilution plate. Alice Brankin, along with Kerri Malone from Zam Iqbal’s group at the EBI, led this work. Share this: Click to share on X (Opens in new window) X Click to share on Bluesky (Opens in new window) Bluesky Click to email a link to a friend (Opens in new window) Email Click to share on LinkedIn (Opens in new window) LinkedIn Click to share on Mastodon (Opens in new window) Mastodon Related antimicrobial resistance clinical microbiology tuberculosis
New preprint: Including minor alleles improves fluoroquinolone resistance prediction 10th November 202217th November 2022 Fluoroquinolones are used to treat both normal and drug resistant tuberculosis and therefore being able… Share this: Click to share on X (Opens in new window) X Click to share on Bluesky (Opens in new window) Bluesky Click to email a link to a friend (Opens in new window) Email Click to share on LinkedIn (Opens in new window) LinkedIn Click to share on Mastodon (Opens in new window) Mastodon Read More
antimicrobial resistance New preprint: predicting rifampicin resistance 16th August 202416th August 2024 In this preprint we train a series of machine learning models on protein mutations found… Share this: Click to share on X (Opens in new window) X Click to share on Bluesky (Opens in new window) Bluesky Click to email a link to a friend (Opens in new window) Email Click to share on LinkedIn (Opens in new window) LinkedIn Click to share on Mastodon (Opens in new window) Mastodon Read More
New preprint: automatically building a better bedaquiline catalogue 31st January 202531st January 2025 A catalogue recording whether individual mutations confer resistance or not to specified antibiotics is a… Share this: Click to share on X (Opens in new window) X Click to share on Bluesky (Opens in new window) Bluesky Click to email a link to a friend (Opens in new window) Email Click to share on LinkedIn (Opens in new window) LinkedIn Click to share on Mastodon (Opens in new window) Mastodon Read More