antimicrobial resistance New paper: detecting compensatory mutations in the RNAP of M. tuberculosis Philip Fowler, 5th February 20245th February 2024 In this paper, by examining testing the association between mutations known to be associate with… Continue Reading
antimicrobial resistance New paper: quantitative measurement of effect of mutations on antibiotics in M. tuberculosis Philip Fowler, 15th January 202415th January 2024 The CRyPTIC project played a major role in the release by the WHO of their… Continue Reading
antimicrobial resistance Updated preprint: predicting pyrazinamide resistance Philip Fowler, 21st November 20238th December 2023 This study was performed by Josh Carter back in 2019 and we uploaded a preprint… Continue Reading
antimicrobial resistance New preprint: compensatory mutations are associated with increased growth in resistant samples of M. tuberculosis. Philip Fowler, 22nd June 20238th December 2023 In this preprint, Viki Brunner shows how, using the large CRyPTIC dataset, she can recapitulate… Continue Reading
New publication: determining novel mechanisms of bedaquiline resistance Philip Fowler, 30th March 20235th April 2023 A new paper with Lindsay Sonnenkalb as first-author has just been published in The Lancet… Continue Reading
New preprint: Including minor alleles improves fluoroquinolone resistance prediction Philip Fowler, 10th November 202217th November 2022 Fluoroquinolones are used to treat both normal and drug resistant tuberculosis and therefore being able… Continue Reading