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Predicting antibiotic resistance de novo

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Fowler Lab
Fowler Lab

Predicting antibiotic resistance de novo

Category: computing

antimicrobial resistance

New preprint: Predicting pyrazinamide resistance in M. tuberculosis using a graph convolutional network

Philip Fowler, 29th October 202529th October 2025

In previous work we’ve used “traditional” machine-learning approaches, like XGBoost, to learn and therefore predict…

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New paper: Evaluating 12 WGS analysis pipelines for MBTC

Philip Fowler, 21st October 202529th October 2025

Ruan Spies did a careful systematic analysis of the publicly-available pipelines that claimed to process…

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antimicrobial resistance

New preprint: rapidly and reproducibly building resistant catalogues for M. tuberculosis

Philip Fowler, 3rd October 20253rd October 2025

The CRyPTIC project carried out many exciting research projects but it never quite got around…

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antimicrobial resistance

New paper: predicting rifampicin resistance via free energy simulation

Philip Fowler, 23rd September 20253rd October 2025

This work was carried out by Xibei Zhang, who is doing her PhD with Peter…

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antimicrobial resistance

New paper: automatically and reproducibly building a catalogue bedaquline resistance-associated variants

Philip Fowler, 18th June 20251st July 2025

Dylan Adlard‘s paper describing how we can rapidly automatically build catalogues of bedaquiline resistance-associated variants…

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antimicrobial resistance

New paper: a deep learning model that reads MICs from images of 96 well plates

Philip Fowler, 26th May 20251st July 2025

Our paper describing how a convolutional neural network model can determine the minimum inhibitory concentrations…

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