antimicrobial resistance New paper: automatically and reproducibly building a catalogue bedaquline resistance-associated variants Philip Fowler, 18th June 20251st July 2025 Dylan Adlard‘s paper describing how we can rapidly automatically build catalogues of bedaquiline resistance-associated variants… Continue Reading
antimicrobial resistance New paper: a deep learning model that reads MICs from images of 96 well plates Philip Fowler, 26th May 20251st July 2025 Our paper describing how a convolutional neural network model can determine the minimum inhibitory concentrations… Continue Reading
antimicrobial resistance New preprint: predicting rifampicin resistance Philip Fowler, 16th August 202416th August 2024 In this preprint we train a series of machine learning models on protein mutations found… Continue Reading
antimicrobial resistance Updating the Grammar for Antimicrobial Resistance Catalogues Philip Fowler, 18th July 202418th July 2024 This blog updates an old (and now out of date) post describing the grammar we’ve… Continue Reading
clinical microbiology New preprint: processing SARS-CoV-2 genetics in the cloud Philip Fowler, 31st January 202431st January 2024 In this preprint, we describe how in July 2022 for two weeks seven sites in… Continue Reading
New publication: Predicting antibiotic resistance in complex protein targets using alchemical free energy methods Philip Fowler, 26th August 202224th October 2022 In this paper, Alice Brankin calculates how different mutations in the DNA gyrase affect the… Continue Reading