antimicrobial resistance New paper: automatically and reproducibly building a catalogue bedaquline resistance-associated variants Philip Fowler, 18th June 20251st July 2025 Dylan Adlard‘s paper describing how we can rapidly automatically build catalogues of bedaquiline resistance-associated variants… Continue Reading
antimicrobial resistance New preprint: looking at rifampicin-resistant subpopulations in clinical samples Philip Fowler, 10th April 202510th April 2025 Since clinical samples are usually grown in a MGIT tube for a while before some… Continue Reading
New preprint: automatically building a better bedaquiline catalogue Philip Fowler, 31st January 202531st January 2025 A catalogue recording whether individual mutations confer resistance or not to specified antibiotics is a… Continue Reading
New preprint: comparing different genetics analysis pipelines for tuberculosis Philip Fowler, 13th January 202513th January 2025 Ruan Spies has done a careful systematic comparison of the current genetics pipelines that purport… Continue Reading
antimicrobial resistance New preprint: predicting rifampicin resistance Philip Fowler, 16th August 202416th August 2024 In this preprint we train a series of machine learning models on protein mutations found… Continue Reading
antimicrobial resistance New paper: Quantitative drug susceptibility testing for M. tuberculosis using unassembled sequencing data and machine learning Philip Fowler, 14th August 202414th August 2024 This is the last paper from the initial set of CRyPTIC publications following the project’s… Continue Reading