New Publication: Predicting whether mutations confer resistance to an antibiotic

Due to the rise of antibiotic resistance, it is increasingly important that your clinician knows which antibiotics will work (and which will not). Traditionally, this is done in hospital microbiology labs by growing a sample taken from the infection site, and then testing how a range of antibiotics affect its

Automated detection of bacterial growth on 96-well plates (AMyGDA)

I am involved in an international collaboration, the Comprehensive Resistance Prediction for Tuberculosis: an International Consortium (CRyPTIC), that is collecting 30-50,000 clinical samples from patients with tuberculosis (TB). Although often viewed as a historical disease, TB kills more people globally than any other infectious disease, with 1.7 million people dying from

New Publication: Protein crowding affects the organisation of ion channels

Protein crowding and lipid complexity influence the nanoscale dynamic organization of ion channels in cell membranes It is difficult to look at the dynamic spatial organisation of ion channels in cell membranes, but this is something coarse-grained molecular dynamics simulations can offer insights. This work, led by Anna Duncan, shows how

2018 PhD projects announced

As described here, one of the main ways of getting funding to studying for a DPhil with me is to apply for an NDM Prize

BashTheBug has won an NIHR Let’s Get Digital Award!

The National Institute for Health Research hold an annual competition, called Let’s Get Digital, to “recognise those people involved in NIHR research using video, photography, websites, infographics and online communities to promote research”. I was encouraged to enter BashTheBug back in June 2017 and was pleased to see in August

Women in Computer Science Day

Last week I ran a small stall at the annual Women in Computer Science day run by the Department of Computer Science at the University

Twitter at #ECCMID

A bit over two years ago I was a guest blogger at the US Biophysical Society Annual Meeting in Baltimore. I was disappointed by the

Diagnosing antibiotic resistance: future trends?

It is Sunday, I’m in Vienna at the European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) congress. As is traditional at all large conventions, Zooniverse Citizen Science project launches today!

My citizen science project, BashTheBug, is launched today. Head over to the website or go straight to the Zooniverse project page and help us start Beta Testing Results

Zooniverse have finished beta-testing my BashTheBug citizen science project. To verify that the task is easy to do and the tutorial and help text understandable, the first version of the project was sent to a number of experienced Zooniverse beta-testers. Over a period of two weeks, 672 volunteers made 34,791

BashTheBug at the Science Museum

A group of us from Modernising Medical Microbiology went to the Science Museum in London to take part in one of their “Lates” events. I

Accelerating Oxford Nanopore basecalling

It looks innocuous sitting on the desk, an Oxford Nanopore MinION, but it can produce a huge data of data from a single sequencing run.