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New publication: detecting minor populations important for predicting fluoroquinolone resistance

When predicting if an infection is resistant or susceptible to a specific antibiotic, it is all too easy to think that the infection is homogeneous and, in fact, many bioinformatic variant callers encourage that point of view. Or, at best, you can subvert the format of, say, a variant call file (VCF) by using the […]

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New preprint: Rapid decontamination of SARS-CoV-2 genetic reads

This preprint describes some software, ReadItAndKeep, that rapidly removes host (i.e. human) genetic information from a sample. This is necessary to ensure that a sample containing SARS-CoV-2 genetic reads cannot be linked to the individual who gave the sample whilst it is being processed by GPAS in the cloud. Martin Hunt and Zam Iqbal did […]