New print: Epidemiological cutoff values for a 96-well broth microdilution plate for M. tuberculosis Philip Fowler, 5th March 202122nd March 2021 0 shares In this preprint, the CRyPTIC project proposes the maximum value of minimum inhibitory concentration (MIC) for 13 different anti-TB drugs below which a sample can be considered to be ‘genotypically wild-type’. It is necessary to establish these values, called epidemiological cutoff values (ECOFFs or ECVs), so that the MICs measured can be converted into binary (resistant/susceptible), or in the case of three drugs ternary (resistant/intermediate/susceptible), predictions. The preprint draws on 20,637 clinical isolates collected by 14 CRyPTIC laboratories based in 11 countries on five continents. Share this:Twitter Related antimicrobial resistance clinical microbiology publication research tuberculosis
antimicrobial resistance Postdoctoral position advertised 17th May 202117th May 2021 Through the CompBioMed2 EU Centre of Excellence project I have funding to appoint a postdoctoral… Share this:Twitter Read More
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citizen science BashTheBug has won an NIHR Let’s Get Digital Award! 4th September 20175th August 2018 The National Institute for Health Research hold an annual competition, called Let’s Get Digital, to… Share this:Twitter Read More