New Publication: Protein crowding affects the organisation of ion channels Philip Fowler, 3rd December 201729th September 2018 0 shares Protein crowding and lipid complexity influence the nanoscale dynamic organization of ion channels in cell membranes It is difficult to look at the dynamic spatial organisation of ion channels in cell membranes, but this is something coarse-grained molecular dynamics simulations can offer insights. This work, led by Anna Duncan, shows how altering the lipid composition of the membrane changes the large-scale organisation of the Kir2.2 channels. Building on some previous work, we also show how the membrane properties, such as stiffness, are also altered. The latter relies on some python code that you can download from GitHub. The paper is free to download. Share this:Twitter Related publication research
antimicrobial resistance New preprint: compensatory mutations are associated with increased growth in resistant samples of M. tuberculosis. 22nd June 20238th December 2023 In this preprint, Viki Brunner shows how, using the large CRyPTIC dataset, she can recapitulate… Share this:Twitter Read More
antimicrobial resistance New preprint: Predicting antibiotic resistance in complex protein targets 4th January 20224th January 2022 In this preprint, which Alice has been working on for several years, we show how… Share this:Twitter Read More
clinical microbiology New publication: Antibody Status and Incidence of SARS-CoV-2 Infection in Health Care Workers 13th January 202113th January 2021 A second Covid-19 publication I’m proud to be (a small) part of has recently published… Share this:Twitter Read More