Members

Alice Brankin

I am studying for a DPhil in Clinical Medicine, supervised by Philip Fowler and Sarah Walker, with funding from the Nuffield Department of Medicine. I previously undertook both Masters and undergraduate degrees in Biochemistry at the university of York. My interests are in protein structure and antibiotic resistance in M. tuberculosis.

 

Dominykas Lukauskis

Dom is doing his Master’s project in the group until March 2019 and he’s working on determining how the free energy of binding of isoniazid to its target, KatG, is influenced by mutations in M. tuberculosis, using molecular dynamics simulations.

 

 

Oliver Adams

Oliver did his first rotation in the group from Jan-Mar 2017 as part of his Interdisciplinary Biosciences DTP DPhil before working in Simon Newstead’s group in Biochemistry learning structural biology techniques. He is supervised by myself and Simon and is working on M. tuberculosis efflux pumps and drug targets until Sept 2020.

 

Philip Fowler

I am a University Research Lecturer working in the Modernising Medical Microbiology group which is part of Experimental Medicine in the Nuffield Department of Medicine at the University of Oxford. I’m based at the John Radcliffe Hospital in Oxford, having moved here in March 2016 from the Department of Biochemistry. For more information, click the links in the menu above or check out my departmental webpages.

 

 


Past Members

Mark Hamblin

Mark was a fourth year (Part II) biochemistry undergraduate and worked on solving the structures of several M.tuberculosis proteins jointly in my group and Simon Newstead’s in Biochemistry.

 

 

Firdaus Samsudin

Firdaus studied for his DPhil, Improving Oral Drug Delivery: Computational Studies of Proton Dependent Oligopeptide Transporters under the supervision of PWF. He published two key papers which you can read about here and here. He is currently working in the group of Prof Syma Khalid at Southampton University.

3 comments

  1. Dear Dr Fowler,

    I have been attempting to use your Python script to analyse a simulation I’ve run. Whilst I do get the expected logarithmic distribution, I am uncertain of the units for the generated data.

    Given that the cited paper i.e. Membrane Stiffness is Modified by Integral Membrane Proteins has not been published yet, I was hoping you could provide an understanding of the results.

    Specifically, what are columns 1, 2, and 3, and what are their units?

    Regards,

    Damien

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